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IJCRR - 3(12), December, 2011
Pages: 17-22
PHYTOCHEMICAL AND ANTIMICROBIAL STUDIES OF THE LEAF EXTRACTS OF BUCHOLZIA CORIACEAE
Author: P. O. Osadebe, G. A. Awemu, K.M.Ezealisiji, M.O.Agbo
Category: Healthcare
Abstract:
Bucholzia coriaceae has been reported in folk medicine to have many medicinal properties
including anthelmentic,antimicrobial and antifungal activity. Phytochemical screening of the
aqueous and methanol extracts of Bucholzia coriaceae leaves revealed the presence of tannins,
reducing sugars, saponins, terpenoids, flavonoids, and cardiac glycosides. The minimum
inhibitory concentration (MIC) of the methanol extract was between 0.5 – 7.0 mg/ml while the
minimum bactericidal concentration (MBC) ranged from 2.0 – 9.0 mg/ml. The methanol and
aqueous extracts exhibited antifungal activity against Candida albicans and Aspergillus niger
with zones of inhibition of 11.5 mm and 3.6 mm for Candida albicans ; 9.0 mm and 2.0 mm
for Aspergillus niger. The aqueous extract exhibited less antimicrobial effect than the
methanol extract.
Keywords: Bucholzia coriaceae, antimicrobial, zone of inhibition
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