Aim: The concept of Pharmacovigilance has been given to keep a watch on ADRs. The science and the activities which relate to the detection, assessment, understanding and the prevention of adverse effects or any other drug-related problems is referred to as Pharmacovigilance.Adverse drug reactions (ADRs) have a major impact on public health as they are associated with significant morbidity and mortality .Healthcare professionals are one of the important pillars of an efficient Pharmacovigilance system because of their contribution in the form of spontaneous reporting.The objective of this study is to assess the awareness of Pharmacovigilance amongst the health care professionals working in NIMS medical college and hospital, Jaipur, India. Methodology: An anonymous questionnaire based survey for health care professionals working in NIMS Hospital, Jaipur was conducted after getting approval from the Institutional Ethical Committee. A structured validated questionnaire consisting of thirteen questions was distributed amongst doctors and residents of all the departments during a single visit to the NIMS Hospital. Results: 150 questionnaires were distributed amongst the doctors of NIMS Hospital after brief description about the study out of which 96 forms were included for evaluation .Hence response rate was 64% (96/150). In our study 66.66 % respondents were males and 33.34% were females. We found that 96% respondents were having knowledge that Pharmacovigilance deals with ADRs and 41.5% respondents had knowledge about the phases of clinical trial and knew that Pharmacovigilance is done in Phase IVof clinical trial. To our surprise only 21% doctors were of the view that all the physicians, dentists, nurses, physiotherapists and even pharmacists can report ADR. Interestingly only 36% doctors were aware of the fact that events related to allopathic drugs, herbal medicines, vaccines and blood products can be reported but maximum doctors thought that only allopathic drug ADRs should be reported. Interestingly 87.5% responders were aware of the National Pharmacovigilance Centre in India but only 16.7% actually reported suspected ADRs to any ADR Reporting centre. Conclusion: To conclude poor knowledge of Pharmacovigilance and underreporting of ADRs in a developing country like India is a matter of great concern and needs prompt intervention.