Objectives: The present study was undertaken to find out whether the __ampersandsignlsquo;general features__ampersandsignrsquo; in the femur by their presence or prominence could aid in its sex determination. Material and Method: 63 femur available at the International Medical School Bangalore were subjectively grouped into 34 male and 29 female femur. The total of the studied features becomes 504 (63x8). The features were graded as single __ampersandsignlsquo;+__ampersandsignrsquo; and double __ampersandsignlsquo;++__ampersandsignrsquo; for their presence or prominence. Results: The presence or prominence of the features in male and female femur was observed to be around 50%. Between the right and left sides, the total was more for the right side for the presence (141/251) or prominence (147/253) of the features. Within the right side, the prominence of the features was more (147/288) and within the left side the presence of the features was more (110/216). For the male femur, the presence (54%) or prominence (58%) of the features was found to be high for right side; within the right it was prominence (50.2%) and within the left (53.3%) it was presence of the features. For the female femur too, the presence (59%) or prominence (58.3%) were found to be high for the right; but, within the right (51.5%) and left (52%) it was the prominence of the features. For male femur, the high scores (22/34) were found for the presence of the medial epicondyle and depth of intercondylar fossa and for female femur, it was the prominence of nutrient foramen (25/29,86.2%). Conclusion: From the present study, it is seen, that the nutrient foramen could be __ampersandsignlsquo;the__ampersandsignrsquo; constant feature in the sex determination of female femur followed by __ampersandsignlsquo;prominence of the features.__ampersandsignrsquo;