Background: Medical students are more prone to stress either due to their rigid standards and high aspiration or due to demanding education. The stress developed in undergraduates continues further in post-graduation and practice resulting in burnout. In India this area is grossly under reported. Therefore the study was carried out with the objective to find out the amount of stressors and its relation to depression. Method: A cross sectional study was carried out with complete enumeration of students present in lecture. They were educated and informed of data collection tool. i.e HESI questionnaire and MDI. Data analysis was done by descriptive and inferential statistic. Result: No difference of level of stressors was found among the students of variable academic years and sexes. 40 % were found to be mildly depressed. All of the Stressors in totality or individual except insufficient feedback and low commitment show significant correlation with MDI scores. Conclusion: Every two student out of five were found to be depressed and it is positively correlated with the stressors like work for future endurance/ capacity, non-supportive climate, faculty shortcoming, workload, financial concern