Background: The penetration of foreign bodies into the hand is generally accepted as a simple injury with the misconception that treatment will be easy. The aim of this study was to analyze the diagnostic and therapeutic challenges during the removal of foreign bodies in hand. Methods: Prospective analysis of patients who had hand injuries caused by foreign body penetration and had been treated in the Department of Orthopaedics from January 2010 to December 2013. Results: The mean age among the 84 patients was 33.03 with standard deviation of __ampersandsignplusmn; 10.98 years, ranging from 14 years to 64 years. Most of them were between the age of 21 and 30 years (43%). About 71.4% (60) of the injured were males. About 69% of foreign body penetrations were occupational injuries. A variety of foreign bodies were isolated from the site of injury; they included metal splinters (33.4%),broken glass (27.4%),broken needles (20%),wood splinters(13%) thorns (5%) and tooth ( 1%). About in 21% (17) of cases the diagnosis of foreign body penetration was missed during the first consultation. Plain radiographs were able to pick up the foreign body in 81% (68) of the cases. In 83.3% of cases local anaesthesia was enough for the extraction of the foreign body. Conclusion: The study gives a clear understanding of the demographics of foreign body penetration and helps to plan in a better way in managing similar cases.__ampersandsignnbsp;