Arterial variations are always very commonly seen in different arteries of the body and they are very important from surgical and diagnostic point of view. Aim of this study is to find variations in the origin and course of vertebral artery. The vertebral arteries are major arteries of the neck. The vertebral arteries and their major branches, i.e. vertebro-basilar system, essentially supply blood to the upper spinal cord, the brain stem and cerebellum and variable parts of posterior cerebral hemispheres. Different types of variations in the origin and course of vertebral artery were found .The operative indications for surgery in the cervical region include spondylosis, a herniated inter-vertebral disc, tumour, infection and trauma. . So, apart from understanding the clinical implications, the data which is derived from the gross anatomical dissections of cadavers can be a useful guideline to the surgeons for careful pre-operative planning in cases with an unusual course of vertebral artery and can help them in avoiding potentially life threatening complications1.