Background: The objective of this study was to study the effect of increased adiposity on Ocular Perfusion Pressure (OPP) and its relation with obesity indices. Methods: The study included 82 subjects grouped into two based on their Body Mass Index (BMI) as obese group (n=41) and Normal group (n=41). Blood Pressure was measured using sphygmomanometer. Mean Arterial Pressure (MAP) was calculated. Intraocular Pressure (IOP) was recorded using Schiotz indentation tonometer after anaesthetizing the cornea with 2% paracaine solution. OPP was calculated as 2/3 the MAP minus IOP, Systolic Ocular Perfusion Pressure (SOPP) was calculated by Systolic Blood Pressure minus IOP and Diastolic Ocular Perfusion Pressure (DOPP) was calculated by Diastolic Blood Pressure minus IOP. Statistical analysis was performed using the SPSS version 19. Results: Resting mean SBP, DBP, MAP, IOP, OPP, SOPP __ampersandsignamp; DOPP were significantly higher (p__ampersandsignlt;0.05) in the obese group. IOP, OPP, SOPP __ampersandsignamp; DOPP were significantly positively correlated with all the obesity indices. BMI was the most important individual parameter in prediction of IOP where as WHR __ampersandsignamp; WC was the major predictors for OPP, SOPP and DOPP. Conclusions: The study thus shows that Ocular perfusion pressures were significantly affected by the increase in adiposity inyoung adults