Introduction: The quantum of biomedical waste generated during diagnosis, treatment, interventions and management of patientscan be minimised and effectively managed if there are continuous surveillance mechanisms and regular audits. One such intensive biomedical waste audit drive was undertaken at our hospital, a 500 bedded hospital in Northwest Delhi. Methodology: A prospective study involving daily audits was carried out by the biomedical waste team including doctors from the department of Microbiology. At the end of every month audit report was discussed in the biomedical waste committee and__ampersandsignnbsp; sent to the Medical Superintendent for necessary action. Results: A total of 280 rounds were taken of different areas in the hospital during a period of 9 months (January __ampersandsignndash;September 2013). The most common problem was improper segregation (19.28%); followed by overfilled sharp containers (3.57%), nonfunctional needle destroyer (3.57%) and non-availability of bags (1.43%). Documentation of biomedical waste generation, segregation and transport was improper in 19.64% areas. Discussion and conclusion: Daily discussions of observations and prompt rectification helped to maintain a constant sense of awareness of the biomedical waste rules and regulations. Proactive measures concerning biomedical waste management, timely interventions and involvement of all the hospital staff go a long way in effective management of health-care waste.