Introduction: Thyroid associated ophthalmopathy is an autoimmune disorder. It is a life -long disease with systemic and ocular manifestations. Early diagnosis and appropriate management of this disorder are essential. Aim: Clinical presentation and management of 100 consecutive cases of Thyroid associated ophthalmopathy seen in the outpatient department of a regional institute of ophthalmology. Material and Methods: All patients of Thyroid associated ophthalmopathyseen in our institute were subjected to a complete clinical work up, ultrasonography B scan, computed tomographic scan, triiodothronine, thyroxine and thyroid stimulating hormone assays. Treatment of thyroid dysfunction and thyroid ophthalmopathy were given as per protocol. Observation and Results: Age of patients ranged from 17-63 years. The female:male ratio was 1.7:1. Distribution of thyroid dysfunction was hyperthyroidism (96%), hypothyroidism(3%) and euthyroid(1%). Majority of patients had mild (68%) and /or quiescent disease(77%). Eyelid retraction was the most common presentation (88%). Other presentations were exophthalmos( 63%), extraocular myopathy(37%), soft tissue inflammation (23%) and optic neuropathy (12%). Thyroid dysfunction was treated with anti thyroid drugs(100%), thyroidectomy(12%), radioactive iodine(1%). Thyroid ophthalmopathy was treated with supportive therapy(100%), glucocorticoids(32%), ocular surgery(27%), orbital radiotherapy (1%), cyclosporine(1%). Conclusion: We present the clinical manifestations and management of Thyroid associated ophthalmopathy patients at a regionalinstitute of ophthalmology. A larger percent of patients required glucocorticoids reflecting the referral of moderate-severe and/or active patients to our tertiary care centre.