Digital images have become an important tool in pathology. Telepathology towards consultation is rapidly developing. Teaching through digital slides is growing fast due to easily availability of digital cameras, computer hardware and the internet. Objective: Our purpose was to evaluate the resolution requirement for digital images. Size of data of these digital images and there upload speed was also evaluated. Methods: Digital images of 29 selected slides showing characteristic lesions were produced in five different resolutions each, ranging from 640x480, 2048x1536, 2592x1944, 3264x2448 and 4000x3000---. They were compared individually by a group of two experienced pathologists regarding the diagnoses and level of confidence. Results: Images at the resolution of 2048x1536 were perceived as equivalent to higher resolutions, Data upload and image loading was significantly better in 2048x1536 rather than 4000x3000 images Conclusion: For digital images in dermatology a resolution of 768 x 512 x 24 is suitable to recognize the relevant details of the source image.