The normal development and growth of various structures in human body gives distinct appearance to the body with proper functions. Growth of individuals mainly depends upon the growth of long bones. Cartilage in epiphyseal end of long bones proliferates to form matrix which gets converted into bone by ossification and calcification. Continuous formation of matrix, conversion of bone helps the longitudinal growth of bone. Various factors disturb the endochondral ossification in various places including the long bones and the growth of bone is disturbed causing stunted growth with deformities in the individual. Thorough study of the facts and truths of disturbances of cartilage growth of long bones and other parts of bone would help in research to find out the possible remedies to solve the problem in cartilage dysfunction. Hence the present article is prepared to review the various aspects of cartilage, cartilage growth disturbances in endochondral ossification, stunted growth and deformities.