Field and laboratory experiments were conducted to evaluate the comparative effects of poultry manure, piggery manure and NPK fertilizer on the growth, yield and nutrient content of Okra (Abelmoschus esculentus) in Umudike southeastern Nigeria. The treatments were: Control (A), 10 tons/ha Piggery manure (B), 10 tons/ha poultry manure (C), 10 tons/ha poultry manure + 100 kg/ha NPK (15:15:15) fertilizer (D), 10 tons/ha Piggery manure + 100 kg/ha NPK (15:15:15) fertilizer (E) and 400 kg/ha NPK (15:15:15) fertilizer (F). The treatments were replicated three times. The experiment was laid out in a randomized complete block design. The test soil was strongly acidic, having a pH (5.0) and low in % total nitrogen, % OC and the exchangeable bases. The okra variety Ivra v 21 was used for the study. From the results obtained from the study, plant height, stem girth and the number of leaves of Okra were significantly (P__ampersandsignlt;0.05) increased over the other treatments by treatment B. However at harvest, treatments C and D gave the highest values of fresh fruit weight and fruit number respectively. The N, P and K contents of the okra was also investigated, but the result obtained could not be attributed to the treatments applied. Treatments C (10tons/ha PM) and D (10tons/ ha PM + 100kg/ha NPK fertilizer) were therefore recommended for profitable Okra (Abelmoschus esculentus) production.