Study Design: Experimental study. Background: The majority of the people experience low back pain at some point in their life. World data reveals 40 % or more people have sciatica due to lumbar disc prolapse mostly in younger adults in association with 50-70% lifetime incidence of low back pain. Objective: To compare the effectiveness of Transcutaneous Electrical Nerve Stimulation and Kati Basti in reducing the Sciatica. Method: Fifty Eight patients with chronic pain were recruited for the study. Investigator explained the study to the patients and obtained an informed consent form and they were divided into two groups such as group A (Transcutaneous Electrical Nerve Stimulation) and group B (Kati Basti).Twenty nine patients were given Transcutaneous Electrical Nerve Stimulation and 29 patients were given Kati Basti for two weeks. Outcome measures were assessed before and after the treatment in both groups. To measure the angle of movement and intensity of pain Straight Leg Raise Test and Visual Analogue Scale were administered respectively before and after the treatment for both groups. Results: The study shows that after two weeks of intervention, there was a significant reduction of pain and improvements in Straight Leg Raise Test in both the groups from baseline. Thus, both interventions were found to be effective in reducing pain for patients with sciatica. However, Transcutaneous Electrical Nerve Stimulation was more effective than Kati Basti in relieving the pain. Conclusion: Both the interventions, Transcutaneous Electrical Nerve Stimulation and Kati Basti, were effective in improving Straight Leg Raise Test and reducing the pain. However, patients in Transcutaneous Electrical Nerve Stimulation have improved more in terms of reduction of pain than in patients who were treated with Kati Basti after two weeks of treatment.