Breast carcinoma in men is an exceedingly rare entity, contributing to 1% of all breast cancers [1], of which invasive lobular carcinoma (ILC) accounts for 1.5% [2]. The average age at diagnosis is usually five years older compared to women [1, 3]. Although the exact aetiology remains unknown, hyperestrogenic states are attributed as the most likely cause [4]. Men with family history of female breast cancer are at 2.5 times more increased risk when compared to those with no family history [5]. Lobular histologic subtype of breast carcinoma in males is rare due to the lack of acini and lobules [6]. Some medications, such as cimetidine [7, 8] are thought to multiply the risk of male breast cancer because they induce a hyperestrogenic state. The authors report a rare case of ILC in a 75 year old man, with no known risk factors for breast cancer. However, he had a history of prolonged self-prescribed ranitidine use for dyspeptic symptoms. Although there isn__ampersandsignrsquo;t enough evidence to suggest that ranitidine, like its predecessor cimetidine, may cause male breast cancer. The authors would like to draw attention to this possibility.