Introduction: Endodontic management of immature permanent teeth is a challenge for both clinicians and researchers. Open apex is an unusual wide apical foramen that results due to multiple reasons such as incomplete development, extensive apical resorption, caries leading to pulpal necrosis or trauma before complete root formation, root-end resection, or due to over instrumentation. Aims: To prevent the risk of subsequent microbial contamination. Case Report: This article is a case report showing the management of open apex with MTA plug and a thermoplasticized Gutta Percha technique for obturation. Discussion: Traditionally, calcium hydroxide was used for inducing the formation of an apical barrier. Conclusion: Currently, biomimetic materials like mineral trioxide aggregate (MTA) and biodentin have shown promising results for apexification procedures.