Introduction: Squamous cell carcinoma of the esophagus is more common than adenocarcinoma. It is most common in Asian countries and more prevalent in black population as compared to white population. Its incidence has a decreasing trend, recent years. This disease is very rarely seen in children and adolescents. Case Report: A 12-year-old boy with moderately differentiated adenocarcinoma of lower esophagus is reported because it is a very rare disease in children. Patient presented with vomiting and dysphagia. Surgery was not possible due to widespread disease. Chemotherapy followed by radiotherapy was given. Patient started taking semisolids after two courses of chemotherapy. Discussion: Esophageal carcinoma is disease of old age and most prevalent in Asian countries. Most patients with this disease are male and have age more than 50 years. This disease is very rarely found in children, the youngest patient presented with the disease was eight years old. It frequently metastasizes to lungs, liver and mediastinal lymph nodes.