Introduction: Rampant caries is the most common chronic childhood disease leading to decreased oral function, undesirable esthetics and consequent malocclusion and psychological problems. Oral rehabilitation under general anesthesia under certain circumstances is the only choice for the comprehensive treatment of extremely young, emotionally immature patients unable to cope with the same on a dental chair. Case Report: This case report describes the challenging task of the full mouth rehabilitation of a 2-year-old patient with rampant caries having severely mutilated maxillary teeth under general anesthesia. Conclusion: Treatment under general anesthesia provides the advantage of providing thorough oral rehabilitation in a limited period of time, allowing immediate pain relief, even with little or no patient cooperation.