Introduction: There are a lot of risks involved with the surgery which include postoperative complications such as ureteric damage and sepsis. With the rise in the need for an efficient cure for expelling ureter stones research is being done to study the effect of medical expulsive therapy on the expulsion of stones. Aim: The purpose of this study was to observe the outcome of ureter stones expelled with medical expulsive therapy Methodology: The study population consisted of a sample of 220 patients that had been diagnosed with Ureterolithiasis. This diagnosis was radiologically confirmed. Once the diagnosis was confirmed, the patients have prescribed medication for the medical expulsive therapy. The medication prescribed was tamsulosin which was to be taken daily over a period of six weeks. Follow-up checkups were used to gauge the pain severity and determine whether the drugs needed to be continued. Surgical intervention was required for patients who had a stone size greater than 10 millimeters. A prospective longitudinal study. This study was conducted at Benazir Bhutto Hospital Rawalpindi Pakistan, a period of six months from December 2020 to May 2021. Results: In a total of 220 patients, 173 (78.6 %) of the patients were male while the rest of the 47 patients (21.4%) were female. The mean age of the patients was 41 __ampersandsignplusmn; 4.3 years. The results showed that a total of 220 stones were found in the patients where 43 stones (19.5 %) were found in the upper ureter, 55 stones (25%) in the mid ureter and 122 stones (55.5%) in the lower ureter. A total of 40% of the patients passed their stones within the 12-weeks. A total of 14% of patients did not expel the stones through Medical expulsive therapy rather they required surgery to remove the stones. The results from the study showed that in cases of uncomplicated Ureterolithiasis, stones that had a size of up to 10 millimeters could be expelled easily through medical expulsive therapy. Conclusion: The study showed that only a small percentage of the patients with ureter stones required surgical intervention and vertical expulsive therapy proved to be an efficient way of expelling the stones up to ten millimeters. The trial could be continued from 6 to 12 weeks dependent on the movement of the stones through the ureter passage.