Introduction: Scleral lenses are gaining popularity in places where contact lenses are fitted. MSCL__ampersandsignrsquo;s sub-group of scleral contact lenses with a total lens diameter between 14 and 18 mm, which rest entirely upon the sclera. Aim: The study aims to evaluate the influence of mini-scleral contact lens (MSCL) wear on corneal shape, thickness, and higher-order aberration after the lens settled on the eye for 4 to 6 hours in non-inflammatory ecstatic corneal disorders. Purpose: The study aims to check the change in corneal curvature and thickness after settling the lens on the eye for 4 to 6 hours. Also, check if there is any change in corneal aberration just after insertion and after settling the lens for 4 to 6 hours. Methods: This study was a prospective Cross-sectional experimental study to prove what was hypothesized in advance. Scheimpflug imaging was done for 15 subjects (mean age 26.4(__ampersandsignplusmn;6.57)), first before insertion of mini-scleral contact lens. Second, just after wearing the mini-scleral contact lens. Third, after 4 to 6 hours of wearing of mini-scleral contact lens. Fourth, just after removal of MSCL in non-inflammatory ecstatic corneal disorder patient. Natural diurnal variations were considered by measuring separate control groups. Results: Small but significant increase in corneal thickness was observed just after removal of the lens after 4 to 6 hours of wearing (from 447.2(__ampersandsignplusmn;46.8) to 457.8(__ampersandsignplusmn;50.35) __ampersandsignmicro;) P=0.023. After 4 to 6 hours of wearing, significant flattening of steep and steepest corneal curvature was observed having mean (0.0524(__ampersandsignplusmn;0.085) mm, 0.933(__ampersandsignplusmn;1.6) D respectively (P=0.032). Conclusion: Increase in corneal thickness, and significant flattening of steep corneal curvature was observed immediately after removing the lens after 4 to 6 hours of wearing. Modern MSCL decreases both higher and lower order aberration immediately after wearing the lens. Modern mini scleral lenses influence the corneal shape and induce small but significant corneal oedema after 4 to 6 hours of wearing.