Introduction: Brachial plexus block is an integral part of the regional anesthetic technique employed in orthopedic surgeries of hand, arm, and shoulder. It is used to circumvent the need for general anesthesia. Aim: The present study aimed to compare the efficacy of ultrasound guidance and nerve stimulation technique for supraclavicular brachial plexus block. Methods: Based on the inclusion criteria and exclusion criteria n=60 patients were identified and selected for the study. They were randomly allocated in two groups of n=30 each by computer-generated random allocation. Group A (US group) will receive ultrasound-guided supraclavicular brachial plexus block and Group B (NS group) will receive nerve stimulator-guided supraclavicular brachial plexus block. Results: The average number of attempts taken to locate supraclavicular brachial plexus in Group A (US) was 1.33 and in Group B (NS) was 5.56 which is statistically significant (p__ampersandsignlt;0.001). The block performance time (BPT) is the time spent for detecting supraclavicular brachial plexus and injecting a local anesthetic (0.75 % Ropivacaine) around it. The mean time taken by Group A(US) was 4.8 __ampersandsignplusmn; 1 minute, while it was 10.3 __ampersandsignplusmn; 1.5 minutes in Group B the p-value calculated was p __ampersandsignlt; 0.001 which is statistically significant. Conclusion: Compared to nerve stimulator-guided technique ultrasound-guided technique has more advantages like a lesser number of attempts required, less block performance time, lesser onset time for sensory and motor block, and longer duration of sensory and motor block, more patient satisfaction and fewer complications.