Introduction: In India, though various studies have been carried out on menopausal symptoms, majority of them were hospital-based. During menopause they experience changes which may affect their quality of life, severity and impact of the symptoms vary extremely from person to person and population to population. Hence this study attempted. Objectives: To assess and determine the factors associate with the quality of life among menopausal women in rural area, Chengalpattu district. Methodology: A community-based cross-sectional study conducted in rural areas of Chengalpattu district for duration of two months among women. 100 women aged 45 to 60 years, were selected by convenient sampling method, who were willing to give a consent were included and those who had regular bleeding were excluded. Primary data were collected using Semi structure questionnaire with MENQOL scale by interview method; analyzed using SPSS 16V. Descriptive statistics Mean, SD and Percentages were calculated and chi square test used to determine the factors at 5% __ampersandsignalpha;. Results: 30% of women attained their menopause before 40 years; 10% were in peri-menopausal period; 18% had Hysterectomy. 35% had vasomotor symptoms; 47% Psychosocial symptoms, 67% physical symptoms and 14% sexual problems. Conclusion: Family support and choice of lifestyle modification along with supportive therapy should be encouraged. These may require intensive health education for pre and menopausal women and for the community at large.