Introduction: Postmenopausal women are those women who have stopped menstrual bleeding one year ago physiologically or as a result of medical or surgical interventions. Postmenopausal women undergo various hormonal, physiological and physical changes. These hormonal changes lead to the development of distressing symptoms including hot flushes, joint pain, sleep disturbances, vaginal dryness, osteoporosis, cardiovascular diseases, etc. The majority of women in India attain menopause with limited knowledge and coping strategies to deal with menopausal symptoms. Lifestyle modification is an easy way to cope up with these menopausal symptoms which involve altering the long term habits, mainly diet, physical activity, etc and maintaining a new behaviour for months or years. Adequate knowledge of lifestyle modification in postmenopausal women can lead to early prevention of menopausal symptoms and complications. Method: This study was conducted in Karad among 94 postmenopausal women belonging to the age group of 45 to 65 years. The participants were selected according to inclusion and exclusion criteria and a self-administered questionnaire was distributed among them and correct responses were calculated according to 5 points Likert scale. Result: The study evaluated that out of 94 participants 13% (12) had good knowledge, 66% (62) had average and 21% (20) had poor knowledge regarding lifestyle modification in the postmenopausal period. Conclusion: This study concluded that most of the postmenopausal women had average knowledge and very few had good knowledge of necessary lifestyle changes to be done after menop