Introduction: A myofascial trigger point (MTrP) is a hyperirritable spot that can give rise to referral pain, local tenderness, muscle weakness, decrease ROM, peripheral and central sensitization. Manual therapy techniques like M.E.T and strain counter strain have been used in combination to treat upper trapezius trigger points. So the study aimed at comparing the clinical efficacies of these two manual therapy techniques for treating upper trapezius myofascial trigger points in patients with mechanical neck pain. Methods: 30 participants from MIP College OPD, who met the inclusion criteria were selected and randomly divided into two groups, with each group consisting of 15 participants after obtaining their consent. After baseline examination, the participants were randomized to receive either MET (Group A) or Strain counter strain (Group B). The outcome of interest like Pain intensity via NPRS, cervical lateral flexion ROM via goniometer, and cervical pain, and disability via neck disability index (NDI) were assessed at baseline __ampersandsignamp; at the end of 4 weeks. Result: MET and Strain-Counterstrain were effective among which MET was significantly more effective in reducing neck pain (Mean 2.20, p__ampersandsignlt;0.0001), increasing cervical lateral flexion ROM (Mean 42.07, p__ampersandsignlt;0.0001), and reducing functional disability (Mean 12.27, p__ampersandsignlt;0.0001). Conclusion: The study concludes that the Muscle energy technique is more effective than the strain counter strain technique in reducing pain, improving lateral CROM, and reducing neck disability due to upper trapezius trigger points.