Introduction: In India, the occurrence of overweight and obesity is increasingly rising in the younger and adult populations. It is a remedial problem that increases the risk of various lifestyle-modifiable diseases. In hypothyroidism, there are also cardiovascular problems __ampersandsignamp; hs-CRP is a marker of systemic inflammation and an interpreter of cardiovascular disease. Therefore a study was planned to find out the correlation of Hypothyroidism with Lipid Levels, hs-CRP and BMI in the study population. Objective: Our objective of the study is to find out the relationship of hypothyroid patients with lipid profile, hs-CRP__ampersandsignamp; BMI Material __ampersandsignamp; Methods: A Hospital-based observational study was carried out in 87 hypothyroid patients. They were divided into two groups obese __ampersandsignamp; nonobese based on the BMI ranges(group 1 BMI __ampersandsignlt;25 (nonobese)) and (group 2 BMI __ampersandsignge;25(obese)). Serum lipid levels, hs-CRP__ampersandsignamp; BMI were estimated in obese __ampersandsignamp; nonobese groups to find out their correlation. Estimation of hs-CRP was done on semi-auto analyzer__ampersandsignamp;lipid profile by auto-analyzer. All the statistical analysis was done by using the Windows-based SPSS statistical Package (Version 21.0) and P- values __ampersandsignlt;0.05 were taken as the level of significance. Results: There was a significant rise in serum Lipids in the obese group. hs-CRP__ampersandsignamp; BMI has significantly increased in obese people also. There was a statistically significant positive correlation found between lipid levels, hs-CRP and BMI in obese people. Conclusion: Significant correlation was found between hs-CRP, lipid profile and BMI of obese people as compared to nonobese.