Introduction: The phytoconstituents have been shown to have a wide range of biological functions with pharmacological implications. However, these phytoconstituents__ampersandsignrsquo; bioavailability is restricted due to poor absorption. The failure of these constituents to access their site of operation before being degraded, as well as their inability to migrate through the small intestine owing to their multi-ring structures and the lipid composition of the intestinal wall, are the main causes of inadequate absorption. Phytosome technology is one of these devices, which incorporates phospholipids into the uniform active ingredients of herbal extracts, effectively increasing the bioavailability of water-soluble phytoactive constituents including flavonoids, phenolics, and hydrophilic compounds. Aim: The aim of the study involves highlighting the latest developments in the area of phytosome drug delivery systems which will help researchers in better understanding the subject. Materials and Methods: Normal databases such as Scopus, PubMed, Google Scholar, and others were combed through to find critical published facts in the form of research articles. Results: This research overview summarizes recent developments in phytosome science, focusing on fundamental principles, characterization techniques, method of development, pharmacotherapeutic uses, marketed drugs, and phytosomes potential prospects. Conclusion: Phytosomes are a form of advanced herbal extract that is more easily absorbed and produces better results than traditional herbal extract. Phytosomes also improved pharmacokinetic and pharmacological parameters, allowing them to be utilized in the treatment of a variety of diseases. The absorption of phytosome in the gastrointestinal tract is significantly higher than that of the individual portion, resulting in a higher plasma level.