Introduction: Polycystic Ovarian Syndrome is an exceptionally common endocrine disorder in women of reproductive age. Studies show that there is an intensive relationship between Insulin __ampersandsignamp; gonadal function and adipose tissue. Rotterdam Criteria classifies PCOS into four major phenotypes. Estimation of Adipokines in patients with irregular menstrual cycles may contribute to the early detection of metabolic abnormalities related to PCOS. Objective: The objective of our study was to identify serum Adiponectinto Resistin (A: R) ratio in different phenotypes of PCOS and assess the possible correlation between the A: R ratio and insulin resistance with relation to androgenic fat. Method: In this Cross-Sectionalstudy, we analyzed fasting Insulin and fasting Glucose to calculate HOMA IR, Adiponectin and Resistinfor a total of 144 female subjects of the reproductive age group(18 -40 Yrs). Subjects were classified into 4 groups as per Rotterdam Criteria Complete PCOS(PCO-COM), PCO with Oligo/Anovulation(PCO-O), Anovulation with Hyperandrogenism(O HA), and PCO with Hyperandrogenism(PCO-HA). Regression analysis was done to find the relation among the study variables. ANOVA was used to analyse the significant variance among the groups. Result: We observed a significant difference for the A: R ratio among the groups with the maximum for PCO-HA (3.15__ampersandsignplusmn;0.43) and lowest for O-HA (1.04__ampersandsignplusmn;0.22). Significant moderate association observed between A:R ratio__ampersandsignamp;Insulin Resistance (r = - 0.41, p __ampersandsignlt;0.05) for study population. Conclusion: Adiponectin to Resistin ratio (A: R) is significantly different among the PCOS phenotypes. The lowest values were observed for the O-HA group which is consistent with a higher value of HOMA IR in the same group. Significant Association between A: R Ratio and HOMA IR observed in the study population.