Introduction: Tuberculosis is one of the most important issues of consideration throughout the world. Every country in the world has a budget for tuberculosis eradication means one can understand the importance of this disease. Aim: The present study was undertaken to correlate the demographic and clinical profile of multidrug-resistant tuberculosis patients. Materials and Methods: The study recruited 30 male and female patients from the respiratory medicine department. Demo graphic data and clinical data were obtained from the medical records department with prior permission from the authorities Results: The majority of the patients studied up to intermediate. The majority of the patients were belonging to the retired group. The majority of patients belongs to the 4-5 lakhs category. The majority of patients showed symptoms of fever. Diabetes is the most commonly observed comorbidity. In both cases, 1+ is more common. Negative cases are more in the patients. Table no 9 presents the total leucocyte count in patients. The majority of cases are in the normal range. Conclusion: The study presents detailed information about the relation between the demographic and clinical information of the patients who are resistant to multiple drugs. Further studies are needed in this area for detailed understanding.