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<article xlink="http://www.w3.org/1999/xlink" dtd-version="1.0" article-type="healthcare" lang="en"><front><journal-meta><journal-id journal-id-type="publisher">IJCRR</journal-id><journal-id journal-id-type="nlm-ta">I Journ Cur Res Re</journal-id><journal-title-group><journal-title>International Journal of Current Research and Review</journal-title><abbrev-journal-title abbrev-type="pubmed">I Journ Cur Res Re</abbrev-journal-title></journal-title-group><issn pub-type="ppub">2231-2196</issn><issn pub-type="opub">0975-5241</issn><publisher><publisher-name>Radiance Research Academy</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">4101</article-id><article-id pub-id-type="doi"/><article-id pub-id-type="doi-url"> http://dx.doi.org/10.31782/IJCRR.2021.131802</article-id><article-categories><subj-group subj-group-type="heading"><subject>Healthcare</subject></subj-group></article-categories><title-group><article-title>Digit Ratio and Arterial Stiffness in Males:__ampersandsignnbsp;A Novel Observation&#13;
</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>M</surname><given-names>Arjun</given-names></name></contrib><contrib contrib-type="author"><name><surname>A</surname><given-names>Vinita</given-names></name></contrib><contrib contrib-type="author"><name><surname>S</surname><given-names>Nitin</given-names></name></contrib><contrib contrib-type="author"><name><surname>BANM</surname><given-names>Naidu</given-names></name></contrib></contrib-group><pub-date pub-type="ppub"><day>26</day><month>09</month><year>2021</year></pub-date><volume>8)</volume><issue/><fpage>16</fpage><lpage>20</lpage><permissions><copyright-statement>This article is copyright of Popeye Publishing, 2009</copyright-statement><copyright-year>2009</copyright-year><license license-type="open-access" href="http://creativecommons.org/licenses/by/4.0/"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.</license-p></license></permissions><abstract><p>Background: Measuring blood pressure is a particularly important vital parameter to assess cardiovascular function. Studies have shown that central aortic pressure is more accurate in predicting Cardiovascular risk __ampersandsignamp; organ damage. Pulse wave velocity is considered to be a gold standard for measuring arterial stiffness. Digit ratio (2D:4D) is a well-established marker for prenatal androgen exposure. It has been associated with many diseases such as CVD, hypertension, autism, personality disorder and even cancer. Objective: Primarily the study was targeted to assess the role of measuring non-invasive aortic blood pressure to determine the vascular status and arterial stiffness and implication of Digit Ratio(2D:4D), Age and Body Mass Index ( BMI) on Central hemo dynamic parameters. Method: 25 healthy male subjects aged between 23 to 41 years was incorporated in this study. Height __ampersandsignamp; Weight were measured with a calibrated stadiometer. Finger lengths were measured directly from the palmer aspect with a digital calliper. Peripheral blood pressures were recorded from all four limbs (bilateral brachial, bilateral ankle) __ampersandsignamp; Pulse wave analysis was carried out with Periscope vascular analyzer. Statistical analysis was done with Microsoft Excel 365 and statistical package provided by www. stats. blue. Results: Peripheral Systolic Blood Pressure appeared to be significantly more than the Central Aortic systolic Pressure. The same observation was not true for the Diastolic pressure. Central Aortic Pulse pressure was found to be significantly low. Re regression analysis showed that there is a significant trend) between Carotid to femoral Pulse wave velocity (PWV) and central aortic systolic pressure. Pulse wave velocity was found to be significantly associated with age and left-hand digit ratio. The difference between measured PWV and Normal predicted PWV is significantly associated with the digit ratio of the right hand. Conclusion: Prenatal androgen exposure may play a significant role in arterial health as finger length ratio /digit ratio (2D:4D) was found to be significantly associated with the extent of arterial stiffness in the subjects.&#13;
</p></abstract><kwd-group><kwd> Digit Ratio</kwd><kwd> Arterial Stiffness</kwd><kwd> Pulse Wave velocity</kwd><kwd> Central Aortic Pressure</kwd><kwd> Prenatal androgen Exposure</kwd></kwd-group></article-meta></front></article>
