Background: Clinical research is necessary for the advancement of better health care. Training in clinical research forms a very important part of medical education. This starts in the second MBBS with an introduction to the basics of clinical research as per their syllabus. To date, very few surveys were done on the knowledge, attitude, perception, and practice of Second MBBS students about clinical research. A Knowledge Attitude Practices survey helps reveal misconceptions regarding the subject chosen. Methodology: After ethics committee approval, a prevalidated questionnaire was administered as a Google Form to the second MBBS students and, data were analyzed using descriptive statistics on Microsoft Excel. Results: Out of 104 students who were sent the questionnaire 89 answered, with a response rate of 85.59%. Knowledge was tested with 10 questions of which 5 were multiple choice and 5 were yes or no response. Knowledge was found to be moderate with a mean percentage score of 55.9%. Perception of the students towards clinical research was found to be a positive one overall, with 10 questions out of 12 having a mean above 3. Only 67.42% of students were aware of the presence of an Institutional Ethics Committee. Conclusion: There is a positive attitude towards clinical research and moderate knowledge but, there are still some misconceptions that can be corrected with structured intervention with aspects of ethical research and also by involving more undergraduate students in minor research projects.