Objectives: To assess knowledge and attitudes about HPV, cervical cancer and its screening among women using a structured questionnaire to obtain information. Methods: A cross: Section interview based survey was conducted in May 2015. Two hundred women attending a well women clinic were asked to complete a questionnaire assessing cervical cancer awareness and specific knowledge about prevention of the disease. Settings: Karpaga Vinayaga Institute of Medical Science and Research Centre. Results: Only 38% of the respondents were aware that cervical cancer is the most common cause of gynecological cancers. 63% were aware that infection is the most common cause of cervical cancer of these 49% said that virus is the cause and 16% of the respondents knew that the virus is Human Papilloma virus(HPV). 78% recognized pap smear as a screening test. In total only 13 out of 200 respondents were aware of HPV Vaccine. Conclusion: The low screening participation among Indian women may be due to limited awareness and knowledge about cervical cancer screening examinations. The universal application of Pap smears in western communities has lead to drastic decline in the number of invasive cancers of the cervix and higher detection of preinvasive lesions . Identification of factors determining participation, incorporating a comprehensive health education programme prior to screening, personal invitations, proximity of clinics to the target women all help in increasing the compliance.