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<article xlink="http://www.w3.org/1999/xlink" dtd-version="1.0" article-type="healthcare" lang="en"><front><journal-meta><journal-id journal-id-type="publisher">IJCRR</journal-id><journal-id journal-id-type="nlm-ta">I Journ Cur Res Re</journal-id><journal-title-group><journal-title>International Journal of Current Research and Review</journal-title><abbrev-journal-title abbrev-type="pubmed">I Journ Cur Res Re</abbrev-journal-title></journal-title-group><issn pub-type="ppub">2231-2196</issn><issn pub-type="opub">0975-5241</issn><publisher><publisher-name>Radiance Research Academy</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">4041</article-id><article-id pub-id-type="doi"/><article-id pub-id-type="doi-url">http://dx.doi.org/10.31782/IJCRR.2021.131617</article-id><article-categories><subj-group subj-group-type="heading"><subject>Healthcare</subject></subj-group></article-categories><title-group><article-title>Study of Association of Hba1c Levels with RDW and MCV in Patients of Type 2 Diabetes Mellitus in a Tertiary Care Center__ampersandsignrdquo;&#13;
</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>S</surname><given-names/></name></contrib><contrib contrib-type="author"><name><surname>S</surname><given-names>Arora</given-names></name></contrib><contrib contrib-type="author"><name><surname>A</surname><given-names>Sharma</given-names></name></contrib><contrib contrib-type="author"><name><surname>IK</surname><given-names>Bali</given-names></name></contrib></contrib-group><pub-date pub-type="ppub"><day>30</day><month>08</month><year>2021</year></pub-date><volume>6)</volume><issue/><fpage>175</fpage><lpage>178</lpage><permissions><copyright-statement>This article is copyright of Popeye Publishing, 2009</copyright-statement><copyright-year>2009</copyright-year><license license-type="open-access" href="http://creativecommons.org/licenses/by/4.0/"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.</license-p></license></permissions><abstract><p>Introduction: Diabetes mellitus is one of the most common metabolic disorders and the degree and duration of hyperglycemia are related to the risk of macro-vascular and micro-vascular complications which are responsible for the morbidity and mortality associated with the disease. HbA1c (glycosylated haemoglobin) is measured as an index of glycemic control over the past 2-3 months. Red cell distribution width (RDW) and mean corpuscular volume (MCV) are components of routine complete blood counts (CBC). Increased HbA1c levels may cause structural and functional changes in the haemoglobin molecule and the red blood cell because of which RDW and MCV may be altered. This study aims to assess the association of HbA1c levels with RDW and MCV in patients with type 2 diabetes mellitus. Methods: A prospective, hospital-based, observational study of 6 months from March 2020 to August 2020 including 104 patients with type 2 diabetes mellitus (both new and previously diagnosed patients undergoing treatment) was done. Diabetes mellitus was diagnosed according to ADA (American Diabetic Association) guidelines- HbA1c__ampersandsignge;6.5% (48 mmol/mol) or FBS__ampersandsignge;126 mg/dl (7.0 mmol/L) or 2 hour postprandial glucose__ampersandsignge; 200 mg/dl (11.1 mmol/L) on oral glucose tolerance test or RBS__ampersandsignge; 200 mg/dl (11.1 mmol/L) with symptoms. Results: Out of the 104 patients, 63 were males (60.6%) and 41 were females (39.4%). Most of the patients (30.8%) were in the age group of 41-50 years followed by 51-60 years(29.7) by There was a significant positive correlation between RDW and HbA1c values (p=0.003) while the other parameters did not show any significant correlation. Interpretation __ampersandsignamp; Conclusion: In the present study we found that as the HbA1c values increased there was a concordant increase in RDW values (p=0.003). More studies, with a larger sample size, will further help to explain the correlation between RDW and HbA1c.&#13;
</p></abstract><kwd-group><kwd> HbA1c</kwd><kwd> RDW</kwd><kwd> MCV</kwd><kwd> Type 2 diabetes mellitus</kwd><kwd> Metabolic disorder</kwd><kwd> Hyperglycemia</kwd></kwd-group></article-meta></front></article>
