Background and Aim of the Work: Population studies on the prevalence of Temporomandibular Disorders (TMD) and its symptoms amongst Nigerians overlap. Hence, this cross-sectional survey study assessed TMD prevalence, its symptoms, and causes among students attending Delta State University in Abraka, Nigeria. Methods: Three hundred and eighty-four students from Delta State University Abraka, Nigeria, were enrolled in this study and completed a self-administered questionnaire consisting of students__ampersandsignrsquo; socio-demographic data and TMD symptoms. Data obtained from the survey were subjected to SPSS. A Chi-square test was used to test sex differences and the relationship between socio-demographic variables and TMD symptoms. Data were presented using pie charts and tables. Results: We recorded a TMD prevalence of 44%. Male had a higher TMD prevalence of 52.4% than females, who had a prevalence of 47.6%. Our findings demonstrated no significant relationship between sex and TMD prevalence, with significant associations between age and TMD symptoms. Pain on chewing was most common and closely followed by limitations in opening the mouth in subjects between 21 and 26 years. Our study demonstrated that TMD is caused by injury to the head and neck and stressful conditions in both sexes. Conclusion: TMD is highly prevalent among students attending Delta State University in Nigeria; its prevalence is higher in males than females, and most subjects experienced pain on chewing. Considering the high prevalence value of TMD recorded in this study, screenings should be recommended for its diagnosis and management.