Introduction: Correlation between simple febrile seizures (FS) and iron deficiency anaemia (IDA) is not conclusive due to diversified results reported in numerous previous studies. Low serum ferritin levels have been shown to reduce the seizure threshold. Simple FS and IDA are particularly common in children aged 6 to 60 months. In India, around 60% of children__ampersandsignrsquo;s have nutritional anaemia predominantly due to iron. Objectives: To find out any correlation between Febrile Seizure and Iron Deficiency Anemia. Method: In this hospital-based observational study, we evaluated 90 children aged 6 to 60 months in two equal groups taking fever with seizures as cases and fever without seizures as controls. The study was conducted in the Department of Pediatrics__ampersandsignrsquo;, IMS __ampersandsignamp; SUM Hospital Bhubaneswar from January to June 2019. Detection of IDA was based on complete blood count, serum iron, total iron-binding capacity and serum transferrin level, which were done in all participants as a part of the routine test for the evaluation of microcytic hypochromic anaemia. Results: IDA was found in 64.4% among fever with the seizure group as compared to 28.8% in the group having a fever without a seizure. Boys outnumbered girls in the febrile seizure group. Upper respiratory tract infection mostly of viral aetiology was the most common cause of fever in both cases (51.1%) and controls (46.5%). We found 64.4% of children in the cases group had IDA as compared to 35.6% in the control group and this was statistically significant (adjusted odds ratio 4.4615, 95% CI 1.8363-10.8402, p=0.001). The Chi-Square test indicated a significant association between IDA and FS (p =0.0007). p __ampersandsignlt;0.05 was considered significant. Conclusions: In this study, there was a statistically significant correlation between IDA and simple FS.