Introduction: Brihatpanchmoola is an integral part of Dashmoola herb which is a combination of ten ayurvedic herbs which are Aegle marmelos (l) Correa, Clerodendrum phlomidis l.f., Oroxylum Indicum (L) Benth. Ex. Kurz, Stereospermum. suaveolens (Rox.) DC, Gmelina Arborea Roxb., Solanum Indicum auct. Non-L, Solanum xanthocarpum Schrad __ampersandsignamp; H., Desmodium gangeticum (L) DC., Uraria picta (Jacq) DC and Tribulus Terrestris. The above-mentioned first five herbs of Dashmoola are collectively called Brihatpanchmoola and it is used traditionally in various ayurvedic formulations like Dashmolarishta, Dashmool ghritam, Chywanprash, Mahanarayan Tail etc. Aim: The present review aims to put together various published reports on Brihatpanchmoolaand analyse them critically. Methodology: Various published literature and researches on individual plants of Brihatpanchmoola species are studied deeply in detail covering their morphological parameters, geographical distribution, chemical constituents and Pharmacological activities. This is perhaps the first such compilation of all the species of Brihatpanchmoola in a single article. Result and Conclusion: The enormous medical significance of Brihatpanchmoola species has resulted in huge demand which has increased the pressure on the natural/wild resources. There is an immediate need to reexamine this species using appropriate scientific procedures.