Introduction: To expand the range of domestic biologically active additives, the composition of dietary supplements __ampersandsignquot;Avena-Uz__ampersandsignquot;__ampersandsignnbsp;was developed, which includes dry extracts of sowing oats and rose hips. As a result of the research, the quality standards of the studied dietary supplement were established. Aims: Study of the specific effectiveness of __ampersandsignquot;Avena-Uz__ampersandsignquot;. Methodology: The study of choleretic activity was carried out according to the generally accepted method of N.P. Skakun and A.N. Oleinik Results: The research results showed that the rate of bile secretion in rats receiving choleretic dietary supplements compared with healthy animals for 4 hours of the experiment significantly increased on average by 25.6%. At the same time, there was an increase in the content of bile acids in bile by 39.8% and cholesterol by 3.1% in comparison with the control animals. Conclusions: The study of the specific efficacy of __ampersandsignquot;Avena-uz__ampersandsignquot;__ampersandsignnbsp;showed that the dietary supplement can stimulate the exocrine function of the liver, and also normalizes cholesterol, triglycerides in the blood, the content of digestive enzymes - alkaline phosphatase and amylase.