Introduction: Accurate fit of the complete denture is the most important factor in prosthodontic practice. The primary contributors for the retention are the good base adaptation of a denture to underlying mucosa and the border seal. Despite the success of acrylic resins as denture base materials, the dimensional changes caused by them must be accepted as one of the disadvantages of acrylic resin dentures. Objectives: The present study aimed to investigate the retention of maxillary complete denture bases made on type III and type V dental stones. Methodology: 15 completely edentulous patients who needed prostheses were included in this study. After primary and secondary impressions, two casts were prepared from the mould, one using the type-III dental stone and another with type-V stone. Thermoplastic resin gaskets of 2 mm in thickness were used to prepare denture bases models on both casts. Heat cure denture bases were fabricated on the prepared casts and retention was measured using an electronic scale. Results: It was observed that the mean retentive force increased up to 30% with denture base made on type V dental stone (mean retentive force 4.46N) than denture base made on type III dental stone (mean retentive force 3.12N). Conclusion: Based on the study findings, it was concluded that denture bases made on type V stone compensated to a substantial degree for the shrinkage of acrylic resin and plays an important role in obtaining the optimum retention of the maxillary complete denture.