<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd">
<article xlink="http://www.w3.org/1999/xlink" dtd-version="1.0" article-type="healthcare" lang="en"><front><journal-meta><journal-id journal-id-type="publisher">IJCRR</journal-id><journal-id journal-id-type="nlm-ta">I Journ Cur Res Re</journal-id><journal-title-group><journal-title>International Journal of Current Research and Review</journal-title><abbrev-journal-title abbrev-type="pubmed">I Journ Cur Res Re</abbrev-journal-title></journal-title-group><issn pub-type="ppub">2231-2196</issn><issn pub-type="opub">0975-5241</issn><publisher><publisher-name>Radiance Research Academy</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">3929</article-id><article-id pub-id-type="doi"/><article-id pub-id-type="doi-url"> http://dx.doi.org/10.31782/IJCRR.2021.131417</article-id><article-categories><subj-group subj-group-type="heading"><subject>Healthcare</subject></subj-group></article-categories><title-group><article-title>Smooth Extubation __ampersandsignndash; Does Morphine Need a Comeback?&#13;
</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>S</surname><given-names>Parthasarathy</given-names></name></contrib><contrib contrib-type="author"><name><surname>VV</surname><given-names>Subramanian</given-names></name></contrib><contrib contrib-type="author"><name><surname>M</surname><given-names>Ravishankar</given-names></name></contrib></contrib-group><pub-date pub-type="ppub"><day>20</day><month>07</month><year>2021</year></pub-date><volume>4)</volume><issue/><fpage>189</fpage><lpage>193</lpage><permissions><copyright-statement>This article is copyright of Popeye Publishing, 2009</copyright-statement><copyright-year>2009</copyright-year><license license-type="open-access" href="http://creativecommons.org/licenses/by/4.0/"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.</license-p></license></permissions><abstract><p>Background: Extubation is a day-to-day procedure in anaesthetic practice with inherent complications; the incidence of de scribed respiratory complications being higher than during intubation. If the procedure of extubation turns out to be choppy, the incidence is furthermore. Methods: A complete search of the databases Cochrane, PubmedScopus with words: extubation, recovery, smooth, morphine was done Results and Discussion: Extubation can be difficult in patients undergoing head and neck surgeries, patients with significant cardiorespiratory illness and those with a high body mass index. Extubation in a deeper plane is not uncommon and has its advantages and disadvantages. The frequent side effects which hinder smooth extubation in a routine case are cardiovascular stimulation, coughing, pain and inadequate narcosis. If we think in the reverse, in the absence of the above-said problems, extubation can be smooth. The process also differs with the type, duration and site of surgery. Polypharmacy with novel drugs like fentanyl, lignocaine and dexmedetomidine is likely to target the adverse issues separately and can still impede smooth extubation. The versatile natural opioid morphine has antitussive, narcotic, hypotensive and bradycardic effects. With a similar respiratory adverse effect profile as multiple doses of fentanyl, the cost-effective drug morphine can very well make a comeback to make extubation smooth. The comprehension of timed and synchronized administration of the reversal agent and withdrawal of the inhalational agent is earned with the rich experience of blending art and science. Conclusion: We opine that morphine as a single drug may effectively do the job of the combination of drugs in achieving smooth extubation.&#13;
</p></abstract><kwd-group><kwd>Anaesthesia</kwd><kwd> General</kwd><kwd> Recovery</kwd><kwd> Extubation</kwd><kwd> Smooth</kwd><kwd> Opioids</kwd><kwd> Morphine</kwd></kwd-group></article-meta></front></article>
