Background: Transfusion of blood components such as Packed Red Cell (PRC), Fresh Frozen Plasma (FFP) and platelet concentrates (PC) play an important role as a supportive therapy. This study was performed to study the utilisation and appropriateness of blood components in clinical practice at a tertiary care hospital__ampersandsignndash;based blood bank at GMC, Jammu. Materials and Methods: A prospective analysis of blood components was conducted over a period of one year from November 2012 to October 2013. The usage of different types of blood component were recorded and correlated with the patient__ampersandsignrsquo;s diagnosis and indications for transfusion. The appropriate use of blood components were assessed by DGHS guidelines. Results: Of the total 17634 units of blood components issued over a period of 1 year, 58.14% were Packed Red Cells (PRC), 29.43% were Fresh Frozen Plasma (FFP), 12.25% were Platelet Concentrate (PC) and 0.18% were Cryoprecipitate. The appropriate use of Packed Red Cells was 90.33% whereas inappropriate use was 9.67%. Inappropriate use of PRC was mostlyseen__ampersandsignnbsp; in patients with minor bleeding without significant changes in hemoglobin level and in patients with asymptomatic chronic anemia with Hb __ampersandsigngt; 7g/dl. For Fresh Frozen Plasma 80.66% usage was appropriate and 19.34% were used inappropriately. Use of FFP for volume expansion was the most frequent form of inappropriate use followed by cases of bleeding without derang of coagulation tests. For Platelet Concentrate 93.29% transfusions were utilized appropriately and 6.71% inappropriately. Inappropriate use of PC was mostly seen in patients who had received platelets prophylactically with platelet count above 10,000/__ampersandsignmu;l. Conclusion: Periodic review of blood component usage is very important to access the blood utilization pattern and judicious implementation of guidelines for use of blood components would decrease their inappropriate use.