Introduction: There is a vast change in healthcare infrastructure in the twenty-first century in India, but still the nation in general and the North-eastern region, in particular, is deprived of its healthcare infrastructure development. In the sense of health indicators like infant mortality, the life expectancy of birth, mortality rate, NER is still poor compared with the other states of India. Poor conditions of health infrastructure create a lot of problems such as non-availability of free medicines for rural poor, nonavailability of good doctors and lack of a sufficient number of government hospitals in rural areas of the country etc. Objectives: The objectives of the study are to analyze the current status of rural healthcare infrastructure in the North- Eastern Region of India and to identify the challenges faced by the rural healthcare infrastructure of North East India. Methods: The paper based on secondary data only. Data has been collected from different source such as Rural Health Statistics (RHS)- 2018-19 published by the Government of India Ministry of Health and Family Welfare Statistics Division, SRS Bulletin published by Office of The Registrar General, India, India HIV Estimates 2019 Report, published by National aids control organization, ICMR __ampersandsignndash; National Institute of Medical Statistics, Ministry of health __ampersandsignamp; family welfare government of India and Database of Government of India (https://data.gov.in). Results: NER of India has a shortfall of an adequate number of SCs, PHCs and CHCs particularly in rural areas as compared to the national average. The study found that the improvement of health care infrastructure in NER of India is unequal and therefore it is unsatisfactory. Conclusion: There is an urgent need to take some policies by the government to establish some new SCs, PHCs in rural parts of the northeastern region of India and also the existing infrastructure needs to be improved through increasing the number of health workers with proper train.