Introduction: Cholelithiasis is the most common health problem in the western population. In this 80% of gallstones contain cholesterol. The pigment stones and mixed stones are remaining 20%. Every subtype having contained bile acids, calcium salt, and components of bile. The prevalence rate of gallstone is 10% to 20% worldwide. But cholelithiasis is found in a different part of the world. In India, the female prevalence rate is 5.59 % than the males 1.99%. South Indians have a 7 times lower occurrence of cholelithiasis as compared to north Indians. Objective: This study is planned to assess the existing level of awareness on the prevention of cholelithiasis in the general population. To evaluate the effectiveness of awareness program on the prevention of cholelithiasis in the general population. To associate the findings of the awareness program on the prevention of cholelithiasis in the general population with selected demographic variables. Methodology - It is an academic-based study. Research approach __ampersandsignndash; Interventional approach use in this study. Research design: One group pre-test post-test design. The study will be conducted in the selected community area of the Wardha district. Sampling technique-probability convenient sampling technique use. Structure questionnaire use. Result: The finding of the study shows that (90.83%) of the general population had an excellent level of awareness score, and (9.17%) had a good level of awareness score. The minimum awareness score in the posttest was 13 and the maximum awareness score in the post-test was 20. The mean awareness score in the post-test was 19.26__ampersandsignplusmn;1.87 and the mean percentage of awareness score in the post-test was 96.33__ampersandsignplusmn;9.36. there was no significant association of awareness score about age education, occupation, Place of residence and diet. Conclusion: The conclusion is drawn on the basic finding of the study, the pre-test finding showed that knowledge of the general population regarding prevention of cholelithiasis inadequate after the planned teaching helped the general population to understand more about prevention of cholelithiasis, most of the general population wear having adequate knowledge after the planned teaching.