Introduction: Recent research has revealed the increased occurrence of anxiety, depression, PTSD and higher stress levels during the ongoing novel coronavirus 2019 (COVID-19) pandemic, similar to those of past epidemics like SARS (Severe Acute Respiratory Syndrome) and Ebola. Objective: This study aimed at assessing the occurrence of anxiety, depression and post-traumatic stress disorder (PTSD) among the general public of Assam during the early phase of the COVID 19 pandemic. Methods: Using quota sampling, data were obtained by emailing questionnaires to the participants. The symptoms of anxiety, depression and stress were assessed by the 21 item version of Depression Anxiety Stress Scales (DASS-21). The symptoms of PTSD were evaluated by using the revised version of the Impact of Events scale (IES R). Results: On analysis by SPSS version 24, among 247 final respondents, using DASS-21, symptoms of anxiety, depression and stress were noted in 29.5 per cent, 29.7percent and 19.7 per cent respondents. The Impact of Events Scale-Revised revealed a clinical concern for PTSD in 43 per cent, a probable diagnosis of PTSD in 26.6 per cent and a high risk of PTSD in 20.1 per cent of the respondents. Students and non-medical professionals were found to be affected to a greater degree, while healthcare professionals showed more severe symptoms of anxiety. Conclusion: Symptoms of anxiety, depression, increased stress and PTSD were noted in the population of Assam during the early phase of the COVID 19 pandemic. Further research in this field with larger sample sizes could aid in planning the neces sary psychiatric interventions and prepare for future pandemics.