Background: COVID-19 is a respiratory ailment spreading from human to human unprecedently bringing about a condition of a pandemic. Rehearsing individual cleanliness is carefully suggested by the U.S. as a prudent step. In any case, to control the ailment spread at the network level there is the need to guarantee an even-handed conveyance of the medicinal services offices among the favoured and oppressed populace of the U.S. Objective: To understand the resource allocation of the healthcare sector in the U.S. and the challenges faced while mitigating the economic impact on the U.S. during COVID-19. Methods: The literature review was performed using databases such as PubMed, Scopus, EBSCO and Google Scholar for the government reports released. Results: Although the U.S. has taken several measures to control the impact of COVID-19 on the population as well as the economy. The underprivileged and some minority groups in the country have been affected by this pandemic. Health insurance plan has been modified in favour of the people so, they could have access to healthcare services. However, in the entire effort of mitigation, the country has faced certain challenges. Compare to the whites, Native Americans, African American and LatinX are facing consequences of the lockdown of the country at a greater intensity. Due to unemployment access to basic necessity was not possible for poor people. The downfall of the economy created a divide in the rural and urban hospitals on the grounds of revenue, availability of health resources and specialists. Conclusion: It is essential to contain and get ready to alleviate further episodes, especially in nations with battling or under-resourced health system framework. As a consequence, marginal propensity to consume and marginal propensity to save comes down to per capita expenditure of individuals on health and medical care hikes.