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<article xlink="http://www.w3.org/1999/xlink" dtd-version="1.0" article-type="healthcare" lang="en"><front><journal-meta><journal-id journal-id-type="publisher">IJCRR</journal-id><journal-id journal-id-type="nlm-ta">I Journ Cur Res Re</journal-id><journal-title-group><journal-title>International Journal of Current Research and Review</journal-title><abbrev-journal-title abbrev-type="pubmed">I Journ Cur Res Re</abbrev-journal-title></journal-title-group><issn pub-type="ppub">2231-2196</issn><issn pub-type="opub">0975-5241</issn><publisher><publisher-name>Radiance Research Academy</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">3775</article-id><article-id pub-id-type="doi"/><article-id pub-id-type="doi-url"> http://dx.doi.org/10.31782/IJCRR.2021.131112</article-id><article-categories><subj-group subj-group-type="heading"><subject>Healthcare</subject></subj-group></article-categories><title-group><article-title>Evaluation of the Hepatoprotective Potential of Adiantum capillus Against Carbon Tetrachloride-Induced Hepatopathy in Rodents&#13;
</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Khan</surname><given-names>Raziuddin</given-names></name></contrib><contrib contrib-type="author"><name><surname>Kaushik</surname><given-names>Madan</given-names></name></contrib><contrib contrib-type="author"><name><surname>Hussain</surname><given-names>Zeashan</given-names></name></contrib></contrib-group><pub-date pub-type="ppub"><day>4</day><month>06</month><year>2021</year></pub-date><volume>1)</volume><issue/><fpage>153</fpage><lpage>158</lpage><permissions><copyright-statement>This article is copyright of Popeye Publishing, 2009</copyright-statement><copyright-year>2009</copyright-year><license license-type="open-access" href="http://creativecommons.org/licenses/by/4.0/"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.</license-p></license></permissions><abstract><p>Introduction: Adiantum capillus (AC) Linn (Family: Adiantaceae) commonly known as __ampersandsignldquo;Hansraj__ampersandsignrdquo; It is used in common cold, cough, pyrexia inflammation, acts as purgative. It improves digestion and renal function. Objective: To investigate the hepato-defensive potential of A. capillus in contradiction of carbon tetrachloride tempted hepatic damage in rats. Methods: The rodents were dosed with 50% ethanolic extract of A. capillus (dose 100, 200, and 300mg/kg. p.o.) against CCl4 induced hepatic damage. Results: CCl4 elevated the level of hepatic markers like SOPT, SGPT, bilirubin and ALP as well as altered the antioxidant enzymes. The level of hepatic biomarkers, as well as antioxidant enzyme, were recovered after the administration of at 100, 200 and 300mg/kg, p.o. among all the doses 300 mg/kg showed the better hepatoprotective potential which was further confirmed by the histopathological. Conclusion: The 50% ethanolic extract of A. capillus (ACE) recover the biochemical as well as antioxidant parameters, which were affected by CCl4. The histopathological analysis supports the outcomes of antioxidants parameters.&#13;
</p></abstract><kwd-group><kwd>Adiantum capillus</kwd><kwd> Hepatoprotective activity</kwd><kwd> SGOT</kwd><kwd> Antioxidant</kwd><kwd> CCl4</kwd><kwd> Histopathology</kwd></kwd-group></article-meta></front></article>
