Background: chronic pelvic pain syndrome is one of the most common diseases in urology, the disease involving discomfort in the perineal area, pelvis, pubic area with ejaculatory and voiding problems. Objective: The main objective of the current study to evaluate the therapeutic effect of Extracorporeal Shockwave Therapy (ESWT), Pulsed Electromagnetic Field Therapy (PEMF) and Drug therapy in treating chronic pelvic pain syndrome. Methods: Seventy-five male patients with chronic prostatitis assigned into three main groups twenty-five for each Group A received Extracorporeal Shockwave Therapy (ESWT) for one month, group B received pulsed electromagnetic therapy for one month and Group C received drug therapy for one month, the treatment plan was pretreatment evaluation by both measures NIH-Chronic Prostatitis Symptom Index (NIH-CPSI) and ultrasonography which were used to evaluate the patients, all were assessed before and after treatment. Results: There was a significant decrease between pre and post values of (shockwave, Pulsed Electromagnetic Field Therapy (PEMF) and Drug Therapy group on the NIH scale and in the US Examination. Conclusion: ESWT is effective in treating non-inflammatory chronic pelvic pain syndrome in men as manifested by a decrease in prostate volume and NIH-CPSI also PEMF and drug therapy are effective in the treatment of chronic prostatitis/chronic pelvic pain syndrome (CP/CPP) but the ESWT is more effective.