Introduction: Hypertensive disorders of pregnancy represent the most common medical complications with increased maternal and perinatal morbidity. Prediction in the first trimester and prevention with aspirin can help to reduce complications. Objective: To find out the ability of uterine artery pulsatility index along with mean arterial pressure (MAP) and body mass index (BMI) for prediction of pregnancy-induced hypertension. Methods: This is a prospective observational study conducted in the Institute of Medical Sciences __ampersandsignamp; SUM Hospital. 200 low-risk pregnant women included at 11-14 weeks of gestation to calculate MAP, BMI. Uterine artery doppler of both arteries are performed during the Nuchal Translucency scan. The average uterine artery pulsatility index was calculated. Result: 7/200 (3.5%) population developed Pregnancy Induced Hypertension( PIH). Mean Arterial Pressure was significantly higher in early-onset Pre-eclampsia (86.65 __ampersandsignplusmn; 3.86) in comparison to normal subjects (80.19 __ampersandsignplusmn; 7.37) with (p= 0.040).BMI was not significantly higher (22.50 __ampersandsignplusmn; 2.32) compared to normal subjects (22.32 __ampersandsignplusmn; 2.02) (p= 0.863). Uterine artery pulsatility index was significantly higher in early-onset pre-eclampsia(p__ampersandsignlt;0.001), late-onset Pre-eclampsia (p= 0.001) and pre-eclampsia(p = __ampersandsignlt;0.001 inclusive of early and late).Body mass index and mean arterial pressure were not significantly different for the prediction of late-onset pre-eclampsia with a p-value of 0.846 and 0.960 respectively. Keeping 95th centile as cutoff (2.5), the detection rate of pre-eclampsia with uterine artery pulsatility index is 71.4% with p __ampersandsignlt;0.001. Conclusion: Combination of uterine artery doppler along with MAP and BMI calculation can effectively screen women at risk of PIH, more so for early-onset PIH before 34 weeks without any extra cost or burden on the health care system.