Introduction: Studied the antiprostatic activity of the sum of esters of sequiterpine alcohols obtained by ferula thin-braided (ferule). Objective: The purpose of the study was to substantiate the feasibility of using the developed new drug ferulene as a means of antiprostatic action in the body. Methods: To assess the effect of ferulene on androgen-dependent organs, the drug was administered to male rats orally using a metal probe at doses of 1-5-10 mg/kg for 10 days. Each dose of the drug was tested on 10 rats. Results: It was found that ferule has a pronounced ant prostatic effect when administered orally, reduces the mass of adreno genesis-dependent organs (ventral prostate, coagulating gland, seminal vesicles, and testes) and reduces the level of testoster one in the blood. In terms of ant prostatic activity, ferule is not inferior to surgical castration. Conclusion: Long-term use of ferulene is well tolerated by experimental animals and does not have a toxic effect on the part of biochemical parameters, a decrease in the mass of androgen-dependent organs (ventral prostate, coagulating gland, seminal vesicles, testes) and a decrease in the content of testosterone in the blood associated with the specific activity of the drug about target organs.