World health organization accepted that antimicrobial resistance is a natural phenomenon, there is an urgent need for comprehensive national plans, based on a multi-sectorial approach and with sustainable financing to fight antimicrobial resistance globally. AMR continues to pose a significant public health problem in terms of mortality and economic loss. Studies related to antimicrobial drugs usage, determining factors and development of antimicrobial drug resistance, provincial discrepancy and interventional strategies is a big challenge for any developing country. This review article aims to highlight the importance of Antibiotic policy and its implementation in every health care system to make physicians, general practitioners, and other stakeholders aware of the issue of AMR and its factors and what can be done. Scoping review was done using ScienceDirect, Web of Science, EconLit, and PubMed. To discuss some of the challenges in the implementation of policies in India such as varied discernments about antibiotic use and AMR among key stakeholders, inappropriate antibiotic use and to achieve the aim of this review was performed by collecting around 80 published articles from 1999 to 2020. Initial suitable antibiotic treatment has been shown to reduce mortality, the span of stay in ICU and hospital. Early correct antibiotic choosen have also served to the reduction in antimicrobial costs. The hospitals which are having antibiotic policy shown decreased morbidity and mortality due to antibioticresistant infections. In developing countries, antimicrobial stewardship programs are emerging up, which will help to develop antibiotic policies for management of infections in various settings. This article focuses on the current status and implementation of antibiotic policy in Indian healthcare settings like the primary, secondary and tertiary hospital to combat antimicrobial resistance.