Introduction: High prevalence of overweight has been found among adolescents in an urban population in developing countries. Physical activity habits track from youth to adulthood, therefore, adolescence may be a critical period for establishing a physically active lifestyle to enhance health and prevent chronic diseases in adulthood. Objective: To compare the effect of fast tempo and slow tempo music during aerobic exercise on cardiovascular endurance (CVE) in overweight adolescents. Methods: This was an interventional study with pre-test- post-test study design. Subjects were assessed using the 20mt Shuttle run test and VO2 max was calculated. The intervention was carried out for four weeks and aerobic exercise in the form of circuit training was administered to 90 overweight adolescents who were divided into 3 groups of 30 subjects each. The same exercise protocol was given with Group A exercising too fast tempo music, Group B to slow tempo music __ampersandsignamp; Group C, the control group, with no music. Results: Intragroup comparison in Group A, B and C showed a highly significant increase in VO2max Intergroup analysis using Anova showed, that the average increase of VO2max in Groups A and C is similar. The results also show that the VO2 max in group B was significantly higher than in Groups A and C. Conclusion: Our findings conclude that exercising with music shows more improvement in VO2 max and slow tempo music shows better results than fast tempo music or no music.