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<article xlink="http://www.w3.org/1999/xlink" dtd-version="1.0" article-type="healthcare" lang="en"><front><journal-meta><journal-id journal-id-type="publisher">IJCRR</journal-id><journal-id journal-id-type="nlm-ta">I Journ Cur Res Re</journal-id><journal-title-group><journal-title>International Journal of Current Research and Review</journal-title><abbrev-journal-title abbrev-type="pubmed">I Journ Cur Res Re</abbrev-journal-title></journal-title-group><issn pub-type="ppub">2231-2196</issn><issn pub-type="opub">0975-5241</issn><publisher><publisher-name>Radiance Research Academy</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">3443</article-id><article-id pub-id-type="doi"/><article-id pub-id-type="doi-url"> http://dx.doi.org/10.31782/IJCRR.2021.13527</article-id><article-categories><subj-group subj-group-type="heading"><subject>Healthcare</subject></subj-group></article-categories><title-group><article-title>Metastatic Lesions Involving Bone Marrow: 16-Year Analytical Study at a Tertiary Care Centre&#13;
</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>S</surname><given-names>Nuzhat</given-names></name></contrib><contrib contrib-type="author"><name><surname>A</surname><given-names/></name></contrib><contrib contrib-type="author"><name><surname>S</surname><given-names>Gull</given-names></name></contrib><contrib contrib-type="author"><name><surname>IH</surname><given-names>Bhat</given-names></name></contrib><contrib contrib-type="author"><name><surname>P</surname><given-names>Hamid</given-names></name></contrib></contrib-group><pub-date pub-type="ppub"><day>3</day><month>03</month><year>2021</year></pub-date><volume>)</volume><issue/><fpage>83</fpage><lpage>86</lpage><permissions><copyright-statement>This article is copyright of Popeye Publishing, 2009</copyright-statement><copyright-year>2009</copyright-year><license license-type="open-access" href="http://creativecommons.org/licenses/by/4.0/"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.</license-p></license></permissions><abstract><p>Introduction: The bone marrow is one of the common organs to be involved by tumours that metastasize via the bloodstream. Screening of the bone marrow is considered one of the most valuable diagnostic tools to evaluate hematologic disorders- diagnosis, staging and therapeutic monitoring. Intracranial tumours rarely metastasize outside the cranial vault. Differences between bone marrow biopsy and aspirate findings usually result from a desmoplastic stromal reaction to the tumour cells that renders neoplastic cells more difficult to aspirate than residual haemopoietic cells. Objective: To know the diagnostic utility of bone marrow aspiration and biopsies in non-haematological lesions which can have a direct impact on treatment and prognosis of the patient. Methods: Bone marrow aspiration and bone marrow biopsy specimens received were dealt with according to the standard procedure for cytological and histological examination. In case of bone marrow biopsies, 5-6 __ampersandsignmicro;m thick sections were cut and stained with routine hematoxylin and eosin stain. Results: In the paediatric age group, the most common metastatic tumour is small round cell tumour among which neuroblastoma is the most common followed by ewings and rhabdomyosarcoma. In adults, most common metastasis was from lung followed by prostate and breast. Lung and prostate were more common in males and breast in females. There was a slight male preponderance in our study with male to female ratio of 1.9:1. Conclusion: The bone marrow examination is a useful, minimally invasive and important investigation in diagnosing metastatic tumours. Further trephine biopsy and bone marrow aspiration are complementary to each other as if one procedure fails to pick up the tumour cells other may diagnose it successfully.&#13;
</p></abstract><kwd-group><kwd> Bone marrow aspiration</kwd><kwd> Bone marrow biopsy</kwd><kwd> Metastasis</kwd></kwd-group></article-meta></front></article>
