Introduction: Traditional medicine is an inseparable part of Indian culture. India has had a rich ethnobotanical heritage. Though much work has been performed to isolate organic compound, a little attention has been given to its inorganic elements. Some inorganic elements play an important role in various physiological processes involved in human health. Elements in excess or deficiency cause several diseases. Objective: To investigate the profile of certain trace elements in C. prostrate. The qualitative and quantitative analysis of trace elements in this plant reveals its herbal properties. Methods: Plant samples were roots, leaves and seeds collected from Srikakulam, Andhra Pradesh and taken for the analysis with the ratio of 1:1:1. IPC-MS has been used to evaluate the composition of liquid and allow high-sensitivity investigation of several metal elements which can be found as the trace. Results: This investigation of plant extracts has been done by using ICP-MS as it is powerful, accurate, fast and sensitive analytical technique. The study gives the presence of various concentrations of important trace elements which are having an essential role in the metabolism of the human body. The analysis results twenty trace elements including Li, Be, Al, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Ga, As, Se, Rb, Sr, Ag, Cs, Ba and Tl. Conclusion: The present investigation deals with trace elements concerning C. prostrate medicinal plant reveals that the elements have significant roles in fighting human ailments and diseases.